Effect of Antihypertensive Medication Reduction vs Usual Care on Short-term Blood Pressure Control in Patients With Hypertension Aged 80 Years and Older. The OPTIMISE Randomized Clinical Trial
James P. Sheppard, Jenni Burt, Mark Lown, Eleanor Temple, Rebecca Lowe, Rosalyn Fraser, et al. for the OPTIMISE Investigators
JAMA. 2020;323(20):2039-2051. doi:10.1001/jama.2020.4871